Induced Progress
When James Thomson’s and Shinya Yamanaka’s research teams published their ground-breaking papers last year on induced pluripotent stem cells, or iPS cells, one of the major hurdles to clinical application was the propensity of the cells to cause cancer. Now, scientists from Harvard University have successfully introduced the pluripotency-inducing genes into mouse somatic cells by way of adenoviruses, which are less harmful than retroviruses.

At the beginning of the month, NIH pulled pooled GWAS data from its website and began encouraging other institutions to follow suit, because a team of scientists have figured out just how to identify a single person’s DNA from a sample of hundreds.
The anti-science forces in Missouri don’t know when to call it quits. This week a state judge decided to hear a lawsuit from the Missouri Roundtable for Life that seeks to block $21 million of state funds from going to the state’s Life Sciences Research Board. The suit may tackle the definitions of reproductive and therapeutic cloning.
What do researchers and clinicians actually need to understand about a gene in order to diagnose and treat patients? Play-by-play from a lively discussion on the state of genetics at the World Science Festival.
The NSF has been making measurable headway in its efforts to improve STEM education from Kindergarten to Grad School and beyond, but it still has a long way to go. On Jan. 15th and 16th the NSF held a conference in DC entitled “Science Education and Workforce Development: Key Challenges for Innovation in the States,” focusing on progress an challenges in the overlapping fields.
New helmet sensors will improve army body armor; the disorganization of state stem cell initiatives; acute stress spikes after 9/11; think tanks for developing nations.
Health coverage inequalities limit patient access to the free drugs pharmaceutical companies distribute, accelerate the illnesses of elderly patients, and limit access to preventative cancer screenings.
The National Research Council of the National Academies convened a symposium Wednesday to explore approaches among “Future Directions in Research at the Intersection of the Physical and Life Sciences.” The intersections up for discussion ranged across the research spectrum: from synthetic biology to geoengineering to bioterrorism.
Healthcare professionals helping patients with mental health problems have an increasing array of treatment and prevention tools at their disposal. But on the horizon is a preventative tool that poses challenging public policy questions about ethics and privacy: personal genomic sequencing.
Advances in nanotechnology may yield myriad powerful technical applications. But to grapple with the gap between research and regulation, the Center on Nanotechnology and Society held its 2nd Annual Conference on Nanopolicy this past Friday.
“A new way to trick skin cells into acting like embryos changes both everything and nothing at all.” Alan I. Leshner and James A. Thomson on the new advances in stem cell research, and other news and commentary from the mainstream press.
Researchers working independently in Japan and the U.S. published papers this week announcing the creation of non-embryonic pluripotent stem cells. The method side-steps the ethical concerns over the destruction of embryos and could open the doors for federal funding of research on stem cells and the medical breakthroughs they promise.